Little Known Facts About cees dekker.
2009, discovery of a new phenotype for microorganisms in slim nanofluidic slits; and initially detection of area protein buildings together DNA applying good-point out nanoporesHuman Rad51 filaments on double- and one-stranded DNA: correlating frequent and irregular sorts with recombination functionality.
To be a individual, I provide the biblical assignment to check out and use anything in development for the advantage of my neighbour. I don't encounter any conflict between religion and science. Quite the opposite, my faith stimulates me to complete science, to be open up-minded on the earth.’
Sculpting nano-electrodes which has a transmission electron beam for electrical and geometrical characterization of nanoparticles.
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and initial ever review of the dynamics DNA supercoils and the discovery of supercoil hopping
In the yrs subsequent these discoveries, my investigate passions shifted to biophysics and nanobiology, And that i became fewer associated with the development of nanotube electronics. The main target of many scientists in the sphere also shifted to graphene (in which, funnily more than enough, the primary graphene ribbons were referred to as ‘nanotubes which have been Lower open up along their size’) just after the discovery of The 2-dimensional product in 2004.
A lot of connected developments followed, wherever our group set up different transistor variants which include solitary-electron transistors at space temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled multiple transistors into smaller proof-of-theory Digital circuits.
Stream-driven rotary motors including windmills and water wheels drive purposeful procedures in human Culture. Though examples of such rotary motors also feature prominently in mobile biology, their synthetic development in the nanoscale has remained tough. Below we demonstrate move-driven rotary movement of the self-organized DNA nanostructure that is certainly docked onto a nanopore in a skinny solid-condition membrane. An elastic DNA bundle self-assembles right into a chiral conformation upon phoretic docking on to the strong-condition nanopore, and subsequently displays a sustained unidirectional rotary motion of up to twenty rev s−1.
‘You should not just contemplate the concerns of tomorrow, but will also look at the concerns with the day soon after tomorrow’
‘The fantastically subtle way during which features in nature operate hardly ever ceases to amaze me. If we resolve the puzzle of how life came into currently being, I expect that my amazement on the complexity of development should have improved and with it my awe for the greatness with the Creator.’
Example (4) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is shown in grey, the rim of the pore is highlighted in red, and a 3D rendering from the motion of the DNA rod is displayed.
2006, 1st demonstration of molecular sorting in a very lab on the chip using biomotors; discovery of nanobubbles in stable-state nanopores; and very first estimate of electrokinetic Power conversion inside a nanofluidic channel
2005, discovery in the system of DNA uncoiling by topoisomerase enzymes; discovery of very long-vary conformational changes in Mre11/DNA cees dekker fix complexes; and 1st pressure measurements over a DNA molecule in a very nanopore
It had been an exceptionally attention-grabbing time, all through which I been given a lot of support from Delft College of Technology, where I was a professor at some time, And that i started off many collaborations with molecular biologists. That aided me understand a good deal.’